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6KUW

Crystal structure of human alpha2C adrenergic G protein-coupled receptor.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Alpha-2C adrenergic receptorpolymer49655508.72Pfam (PF00001)
UniProt (by SIFTS) (P18825)
UniProt (by SIFTS) (Q9V2J8)
Homo sapiens
2C, L
(A, B)
(8~{a}~{R},12~{a}~{S},13~{a}~{R})-12-ethylsulfonyl-3-methoxy-5,6,8,8~{a},9,10,11,12~{a},13,13~{a}-decahydroisoquinolino[2,1-g][1,6]naphthyridinenon-polymer364.52Chemie (E33)
3D, M
(A, B)
CHOLESTEROLnon-polymer386.72Chemie (CLR)
4E, F, G, H, I...
(A, B)
(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoatenon-polymer356.57Chemie (OLC)
5J, K
(A)
OLEIC ACIDnon-polymer282.52Chemie (OLA)
6P, Q
(A, B)
waterwater18.02Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight111017.3
Non-Polymers*Number of molecules13
Total formula weight4563.0
All*Total formula weight115580.3
*Water molecules are not included.

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PDB entries from 2026-02-11

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