6KR4

Crystal structure of the liprin-alpha3_SAM123/LAR_D1D2 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Receptor-type tyrosine-protein phosphatase F	polymer	580	66584.6	4	UniProt (P10586) Pfam (PF00102) In PDB	Homo sapiens (Human)	Leukocyte common antigen related,LAR
2	E, F, H, G	Liprin-alpha-3	polymer	325	36935.9	4	UniProt (P60469) Pfam (PF00536) Pfam (PF07647) In PDB	Mus musculus (Mouse)	Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3,PTPRF-interacting protein alpha-3
3	A, B, C	TETRAETHYLENE GLYCOL	non-polymer		194.2	3	Chemie (PG4)
4	A, B, C, D, E	PHOSPHATE ION	non-polymer		95.0	5	Chemie (PO4)
5	C, D	TRIETHYLENE GLYCOL	non-polymer		150.2	2	Chemie (PGE)
6	D	HEXAETHYLENE GLYCOL	non-polymer		282.3	1	Chemie (P6G)
7		water	water		18.0	161	Chemie (HOH)

Sequence modifications

A, B, C, D: 1332 - 1907 (UniProt: P10586)

PDB	External Database	Details
His 1328	-	expression tag
Met 1329	-	expression tag
Gly 1330	-	expression tag
Ser 1331	-	expression tag

E, F, H, G: 806 - 1126 (UniProt: P60469)

PDB	External Database	Details
Gly 802	-	expression tag
Pro 803	-	expression tag
Gly 804	-	expression tag
Ser 805	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	414082.4
Non-Polymers*	Number of molecules	11
	Total formula weight	1640.2
All*	Total formula weight	415722.6

*Water molecules are not included.