6KR4
Crystal structure of the liprin-alpha3_SAM123/LAR_D1D2 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Receptor-type tyrosine-protein phosphatase F | polymer | 580 | 66584.6 | 4 | UniProt (P10586) Pfam (PF00102) | Homo sapiens (Human) | Leukocyte common antigen related,LAR |
| 2 | E, F, G, H (E, F, H, G) | Liprin-alpha-3 | polymer | 325 | 36935.9 | 4 | UniProt (P60469) Pfam (PF00536) Pfam (PF07647) | Mus musculus (Mouse) | Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3,PTPRF-interacting protein alpha-3 |
| 3 | I, K, M (A, B, C) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 3 | Chemie (PG4) | |||
| 4 | J, L, O, R, S (A, B, C, D, E) | PHOSPHATE ION | non-polymer | 95.0 | 5 | Chemie (PO4) | |||
| 5 | N, Q (C, D) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 2 | Chemie (PGE) | |||
| 6 | P (D) | HEXAETHYLENE GLYCOL | non-polymer | 282.3 | 1 | Chemie (P6G) | |||
| 7 | T, U, V, W, X... (A, B, C, D, E...) | water | water | 18.0 | 161 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1332 - 1907 (UniProt: P10586)
E, F, H, G: 806 - 1126 (UniProt: P60469)
| PDB | External Database | Details |
|---|---|---|
| His 1328 | - | expression tag |
| Met 1329 | - | expression tag |
| Gly 1330 | - | expression tag |
| Ser 1331 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 802 | - | expression tag |
| Pro 803 | - | expression tag |
| Gly 804 | - | expression tag |
| Ser 805 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 414082.4 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1640.2 | |
| All* | Total formula weight | 415722.6 |
