Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| A | 0006470 | biological_process | protein dephosphorylation |
| A | 0016311 | biological_process | dephosphorylation |
| B | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| B | 0006470 | biological_process | protein dephosphorylation |
| B | 0016311 | biological_process | dephosphorylation |
| C | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| C | 0006470 | biological_process | protein dephosphorylation |
| C | 0016311 | biological_process | dephosphorylation |
| D | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| D | 0006470 | biological_process | protein dephosphorylation |
| D | 0016311 | biological_process | dephosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue PG4 A 2001 |
| Chain | Residue |
| A | ILE1819 |
| A | GLY1820 |
| A | HIS1823 |
| A | SER1853 |
| A | LEU1856 |
| A | GLU1857 |
| A | TYR1898 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue PO4 A 2002 |
| Chain | Residue |
| A | GLU1470 |
| A | PRO1465 |
| A | ALA1466 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue PG4 B 2001 |
| Chain | Residue |
| B | ILE1819 |
| B | HIS1823 |
| B | GLU1827 |
| B | SER1853 |
| B | GLU1857 |
| B | TYR1898 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue PO4 B 2002 |
| Chain | Residue |
| B | GLN1462 |
| B | ALA1466 |
| B | GLU1470 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue PG4 C 2001 |
| Chain | Residue |
| C | HIS1823 |
| C | GLU1827 |
| C | SER1853 |
| C | GLU1857 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue PGE C 2002 |
| Chain | Residue |
| C | GLN1417 |
| C | ASN1418 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 C 2003 |
| Chain | Residue |
| C | GLN1462 |
| C | PRO1465 |
| C | ALA1466 |
| C | GLU1470 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue P6G D 2001 |
| Chain | Residue |
| D | HIS1823 |
| D | LYS1824 |
| D | GLU1827 |
| D | SER1853 |
| D | GLU1857 |
| D | TYR1898 |
| H | GLY812 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue PGE D 2002 |
| Chain | Residue |
| A | TYR1381 |
| A | ASN1383 |
| A | TYR1589 |
| A | GLN1592 |
| D | LEU1539 |
| D | ASP1540 |
| D | ALA1541 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue PO4 D 2003 |
| Chain | Residue |
| D | GLN1462 |
| D | TRP1464 |
| D | PRO1465 |
| D | ALA1466 |
| D | GLU1470 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 E 1201 |
| Chain | Residue |
| E | THR1033 |
| E | GLN1034 |
| E | ARG1045 |
| E | TRP1049 |
Functional Information from PROSITE/UniProt
| site_id | PS00383 |
| Number of Residues | 11 |
| Details | TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. VHCsaGvgRTG |
| Chain | Residue | Details |
| A | VAL1546-GLY1556 | |
| A | VAL1837-GLY1847 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| E | SER1123 | |
| F | SER1123 | |
| H | SER1123 | |
| G | SER1123 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | ACT_SITE: Phosphocysteine intermediate => ECO:0000250 |
| Chain | Residue | Details |
| A | CYS1839 | |
| B | CYS1839 | |
| C | CYS1839 | |
| D | CYS1839 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | ASP1516 | |
| D | ASP1516 | |
| D | CYS1548 | |
| D | GLN1592 | |
| A | CYS1548 | |
| A | GLN1592 | |
| B | ASP1516 | |
| B | CYS1548 | |
| B | GLN1592 | |
| C | ASP1516 | |
| C | CYS1548 | |
| C | GLN1592 | |
