6KR3

Crystal structure of Dengue virus nonstructural protein NS5 (form 2)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Genome polyprotein	polymer	911	104543.0	2	UniProt (Q91H74) Pfam (PF01728) Pfam (PF00972) Pfam (PF20483)	Dengue virus 2
2	C, D, E, F, G... (A, B)	IODIDE ION	non-polymer		126.9	15	Chemie (IOD)
3	O, P, X, Y (A, B)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	4	Chemie (SAH)
4	AA, Q, R, Z (B, A)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
5	BA, CA, DA, S, T (B, A)	GLYCEROL	non-polymer		92.1	5	Chemie (GOL)
6	EA, FA (A, B)	water	water		18.0	47	Chemie (HOH)

Sequence modifications

A, B: 1 - 900 (UniProt: Q91H74)

PDB	External Database	Details
Met 0	-	initiating methionine
Gly 901	-	expression tag
Ser 902	-	expression tag
Ser 903	-	expression tag
Ser 904	-	expression tag
His 905	-	expression tag
His 906	-	expression tag
His 907	-	expression tag
His 908	-	expression tag
His 909	-	expression tag
His 910	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	209086.1
Non-Polymers*	Number of molecules	28
	Total formula weight	4163.3
All*	Total formula weight	213249.4

*Water molecules are not included.