6KMV
caspase-11 C254A P22/P10 in complex with mouse GSDMD-C domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Caspase-4 | polymer | 161 | 18030.6 | 1 | UniProt (P70343) Pfam (PF00656) | Mus musculus (Mouse) | CASP-4,Caspase-11,CASP-11,Protease ICH-3 |
| 2 | B, V (B, V) | Caspase-4 | polymer | 167 | 18870.6 | 2 | UniProt (P70343) Pfam (PF00656) | Mus musculus (Mouse) | CASP-4,Caspase-11,CASP-11,Protease ICH-3 |
| 3 | C, G, O (C, G, O) | Gasdermin-D | polymer | 198 | 21497.5 | 3 | UniProt (Q9D8T2) Pfam (PF17708) | Mus musculus (Mouse) | Gasdermin domain-containing protein 1 |
| 4 | BA, D, FA, K, S... (D, K, S, T, W...) | Gasdermin-D | polymer | 197 | 21426.4 | 7 | UniProt (Q9D8T2) Pfam (PF17708) | Mus musculus (Mouse) | Gasdermin domain-containing protein 1 |
| 5 | DA, E, F, Z (E, F, Z, d) | Caspase-4 | polymer | 166 | 18783.5 | 4 | UniProt (P70343) Pfam (PF00656) | Mus musculus (Mouse) | CASP-4,Caspase-11,CASP-11,Protease ICH-3 |
| 6 | H (H) | Gasdermin-D | polymer | 191 | 20702.7 | 1 | UniProt (Q9D8T2) Pfam (PF17708) | Mus musculus (Mouse) | Gasdermin domain-containing protein 1 |
| 7 | I, M, N, Q, Y (I, M, N, Q, Y) | Caspase-4 | polymer | 165 | 18682.4 | 5 | UniProt (P70343) Pfam (PF00656) | Mus musculus (Mouse) | CASP-4,Caspase-11,CASP-11,Protease ICH-3 |
| 8 | J (J) | Caspase-4 | polymer | 149 | 16744.1 | 1 | UniProt (P70343) Pfam (PF00656) | Mus musculus (Mouse) | CASP-4,Caspase-11,CASP-11,Protease ICH-3 |
| 9 | EA, L, P (L, P, e) | Gasdermin-D | polymer | 214 | 23225.4 | 3 | UniProt (Q9D8T2) Pfam (PF17708) | Mus musculus (Mouse) | Gasdermin domain-containing protein 1 |
| 10 | CA, R (R, c) | Caspase-4 | polymer | 150 | 16831.2 | 2 | UniProt (P70343) Pfam (PF00656) | Mus musculus (Mouse) | CASP-4,Caspase-11,CASP-11,Protease ICH-3 |
| 11 | U (U) | Caspase-4 | polymer | 165 | 18654.4 | 1 | UniProt (P70343) Pfam (PF00656) | Mus musculus (Mouse) | CASP-4,Caspase-11,CASP-11,Protease ICH-3 |
| 12 | X (X) | Gasdermin-D | polymer | 199 | 21568.6 | 1 | UniProt (Q9D8T2) Pfam (PF17708) | Mus musculus (Mouse) | Gasdermin domain-containing protein 1 |
| 13 | AA (a) | Gasdermin-D | polymer | 196 | 21311.3 | 1 | UniProt (Q9D8T2) Pfam (PF17708) | Mus musculus (Mouse) | Gasdermin domain-containing protein 1 |
| 14 | GA, HA, IA, JA, KA... (g, h, i, j, k...) | Caspase-4 | polymer | 88 | 10283.8 | 15 | UniProt (P70343) Pfam (PF00656) | Mus musculus (Mouse) | CASP-4,Caspase-11,CASP-11,Protease ICH-3 |
| 15 | SA (s) | Caspase-4 | polymer | 87 | 10212.8 | 1 | UniProt (P70343) Pfam (PF00656) | Mus musculus (Mouse) | CASP-4,Caspase-11,CASP-11,Protease ICH-3 |
Sequence modifications
A: 118 - 278 (UniProt: P70343)
B, V: 101 - 267 (UniProt: P70343)
E, F, Z, d: 101 - 266 (UniProt: P70343)
I, M, N, Q, Y: 102 - 266 (UniProt: P70343)
J: 118 - 266 (UniProt: P70343)
R, c: 118 - 267 (UniProt: P70343)
U: 101 - 265 (UniProt: P70343)
| PDB | External Database | Details |
|---|---|---|
| Ala 254 | Cys 254 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ala 254 | Cys 254 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ala 254 | Cys 254 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ala 254 | Cys 254 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ala 254 | Cys 254 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ala 254 | Cys 254 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ala 254 | Cys 254 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 48 |
| Total formula weight | 805585.2 | |
| All* | Total formula weight | 805585.2 |
