6KMU

P22/P10 complex of caspase-11 mutant C254A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E (A, E)	Caspase-4	polymer	184	20783.8	2	UniProt (P70343) Pfam (PF00656)	Mus musculus (Mouse)	CASP-4,Caspase-11,CASP-11,Protease ICH-3
2	B, F, H (B, F, H)	Caspase-4	polymer	86	10113.6	3	UniProt (P70343) Pfam (PF00656)	Mus musculus (Mouse)	CASP-4,Caspase-11,CASP-11,Protease ICH-3
3	C (C)	Caspase-4	polymer	185	20884.9	1	UniProt (P70343) Pfam (PF00656)	Mus musculus (Mouse)	CASP-4,Caspase-11,CASP-11,Protease ICH-3
4	D (D)	Caspase-4	polymer	87	10212.8	1	UniProt (P70343) Pfam (PF00656)	Mus musculus (Mouse)	CASP-4,Caspase-11,CASP-11,Protease ICH-3
5	G (G)	Caspase-4	polymer	154	17408.0	1	UniProt (P70343) Pfam (PF00656)	Mus musculus (Mouse)	CASP-4,Caspase-11,CASP-11,Protease ICH-3
6	I, J, K, L, M... (A, B, C, D, E...)	water	water		18.0	364	Chemie (HOH)

Sequence modifications

A, E: 102 - 285 (UniProt: P70343)

PDB	External Database	Details
Ala 254	Cys 254	engineered mutation

C: 101 - 285 (UniProt: P70343)

PDB	External Database	Details
Ala 254	Cys 254	engineered mutation

G: 101 - 254 (UniProt: P70343)

PDB	External Database	Details
Ala 254	Cys 254	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	120414.1
All*	Total formula weight	120414.1

*Water molecules are not included.