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6KMU

P22/P10 complex of caspase-11 mutant C254A

Functional Information from GO Data
ChainGOidnamespacecontents
A0004197molecular_functioncysteine-type endopeptidase activity
A0006508biological_processproteolysis
A0008234molecular_functioncysteine-type peptidase activity
B0004197molecular_functioncysteine-type endopeptidase activity
B0006508biological_processproteolysis
B0008234molecular_functioncysteine-type peptidase activity
C0004197molecular_functioncysteine-type endopeptidase activity
C0006508biological_processproteolysis
C0008234molecular_functioncysteine-type peptidase activity
D0004197molecular_functioncysteine-type endopeptidase activity
D0006508biological_processproteolysis
D0008234molecular_functioncysteine-type peptidase activity
E0004197molecular_functioncysteine-type endopeptidase activity
E0006508biological_processproteolysis
E0008234molecular_functioncysteine-type peptidase activity
F0004197molecular_functioncysteine-type endopeptidase activity
F0006508biological_processproteolysis
F0008234molecular_functioncysteine-type peptidase activity
G0004197molecular_functioncysteine-type endopeptidase activity
G0006508biological_processproteolysis
G0008234molecular_functioncysteine-type peptidase activity
H0004197molecular_functioncysteine-type endopeptidase activity
H0006508biological_processproteolysis
H0008234molecular_functioncysteine-type peptidase activity
Functional Information from PROSITE/UniProt
site_idPS01121
Number of Residues15
DetailsCASPASE_HIS Caspase family histidine active site. HqtsdStfLvLMSHG
ChainResidueDetails
CHIS193-GLY207
AHIS193-GLY207
GHIS193-GLY207

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsActive site: {"evidences":[{"source":"UniProtKB","id":"P29466","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues3
DetailsActive site: {"evidences":[{"source":"UniProtKB","id":"P49662","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues3
DetailsModified residue: {"description":"(Microbial infection) ADP-riboxanated arginine","evidences":[{"source":"PubMed","id":"34671164","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

240971

PDB entries from 2025-08-27

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