6KK0
Crystal structure of PDE4D catalytic domain complexed with compound 4e
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | polymer | 326 | 37578.6 | 2 | UniProt (Q08499) Pfam (PF00233) In PDB | Homo sapiens (Human) | DPDE3,PDE43 |
| 2 | A, B | 7-[8-methoxy-2,2-dimethyl-7-(3-methylbut-2-enyl)-5-oxidanyl-6-oxidanylidene-pyrano[3,2-b]xanthen-9-yl]oxyheptanoic acid | non-polymer | 536.6 | 2 | Chemie (M36) | |||
| 3 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | water | water | 18.0 | 299 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 75157.2 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1252.7 | |
| All* | Total formula weight | 76409.8 |
