6KJZ

Crystal structure of PDE4D catalytic domain complexed with compound 1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	polymer	328	37835.9	2	UniProt (Q08499) Pfam (PF00233) In PDB	Homo sapiens (Human)	DPDE3,PDE43
2	A, B	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
3	A, B	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4	A, B	5,9-dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methylbut-2-en-1-yl)-3,4-dihydro-2H,6H-pyrano[3,2-b]xanthen-6-one	non-polymer		410.5	2	Chemie (MKU)
5		water	water		18.0	278	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	75671.8
Non-Polymers*	Number of molecules	6
	Total formula weight	1000.3
All*	Total formula weight	76672.2

*Water molecules are not included.