6KGB

Crystal structure of E61K mutated transthyretin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Transthyretin	polymer	158	17181.5	2	UniProt (P02766) Pfam (PF00576) In PDB	Homo sapiens (Human)	ATTR,Prealbumin,TBPA
2	A	CALCIUM ION	non-polymer		40.1	1	Chemie (CA)
3		water	water		18.0	163	Chemie (HOH)

Sequence modifications

A, B: -19 - 126 (UniProt: P02766)

PDB	External Database	Details
Met -31	-	expression tag
Arg -30	-	expression tag
Gly -29	-	expression tag
Ser -28	-	expression tag
His -27	-	expression tag
His -26	-	expression tag
His -25	-	expression tag
His -24	-	expression tag
His -23	-	expression tag
His -22	-	expression tag
Gly -21	-	expression tag
Ser -20	-	expression tag
Lys 61	Glu 81	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	34362.9
Non-Polymers*	Number of molecules	1
	Total formula weight	40.1
All*	Total formula weight	34403.0

*Water molecules are not included.