6KCN
Crystal structure of plasmodium lysyl-tRNA synthetase in complex with a cladosporin derivative 4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Lysine--tRNA ligase | polymer | 516 | 59781.1 | 4 | UniProt (W7JP72) Pfam (PF01336) Pfam (PF00152) | Plasmodium falciparum (isolate NF54) | Lysyl-tRNA synthetase |
| 2 | E, H, K, O (A, B, C, D) | 3-[[(1~{S},3~{S})-3-methylcyclohexyl]methyl]-6,8-bis(oxidanyl)isochromen-1-one | non-polymer | 288.3 | 4 | Chemie (D5F) | |||
| 3 | F, I, L, M (A, B, C) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 4 | G, J, N, P (A, B, C, D) | LYSINE | non-polymer | 147.2 | 4 | Chemie (LYS) | |||
| 5 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 880 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 77 - 583 (UniProt: W7JP72)
| PDB | External Database | Details |
|---|---|---|
| Met 76 | - | initiating methionine |
| Gly 584 | - | expression tag |
| Gly 585 | - | expression tag |
| His 586 | - | expression tag |
| His 587 | - | expression tag |
| His 588 | - | expression tag |
| His 589 | - | expression tag |
| His 590 | - | expression tag |
| His 591 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 239124.5 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2110.5 | |
| All* | Total formula weight | 241235.0 |
