6KB8
X-ray structure of human PPARalpha ligand binding domain-GW7647 co-crystals obtained by cross-seeding
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Peroxisome proliferator-activated receptor alpha | polymer | 273 | 30856.1 | 1 | UniProt (Q07869) Pfam (PF00104) In PDB | Homo sapiens (Human) | PPAR-alpha,Nuclear receptor subfamily 1 group C member 1 |
| 2 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 3 | A | 2-[(4-{2-[(4-cyclohexylbutyl)(cyclohexylcarbamoyl)amino]ethyl}phenyl)sulfanyl]-2-methylpropanoic acid | non-polymer | 502.8 | 1 | Chemie (2VN) | |||
| 4 | water | water | 18.0 | 143 | Chemie (HOH) |
Sequence modifications
A: 200 - 468 (UniProt: Q07869)
| PDB | External Database | Details |
|---|---|---|
| Gly 196 | - | expression tag |
| Ser 197 | - | expression tag |
| His 198 | - | expression tag |
| Met 199 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30856.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 594.8 | |
| All* | Total formula weight | 31450.9 |
