6K7Y
Intact human mitochondrial calcium uniporter complex with MICU1/MICU2 subunits
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, K... (A, B, C, D, N...) | Calcium uniporter protein, mitochondrial | polymer | 276 | 32300.2 | 8 | UniProt (Q8NE86) Pfam (PF04678) | Homo sapiens (Human) | HsMCU,Coiled-coil domain-containing protein 109A |
| 2 | E, F, G, H, O... (E, F, G, H, R...) | Essential MCU regulator, mitochondrial | polymer | 54 | 5993.2 | 8 | UniProt (Q9H4I9) Pfam (PF10161) | Homo sapiens (Human) | Single-pass membrane protein with aspartate-rich tail 1,mitochondrial |
| 3 | I, S (I, V) | Calcium uptake protein 1, mitochondrial | polymer | 476 | 54432.3 | 2 | UniProt (Q9BPX6) Pfam (PF13202) | Homo sapiens (Human) | Atopy-related autoantigen CALC,ara CALC,Calcium-binding atopy-related autoantigen 1 |
| 4 | J, T (J, W) | Calcium uptake protein 2, mitochondrial | polymer | 336 | 39852.7 | 2 | UniProt (Q8IYU8) | Homo sapiens (Human) | EF-hand domain-containing family member A1 |
| 5 | HA, U (N, A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 6 | BA, GA, IA, LA, OA... (C, H, N, O, P...) | CARDIOLIPIN | non-polymer | 1464.0 | 8 | Chemie (CDL) | |||
| 7 | AA, CA, DA, EA, FA... (B, C, D, N, O...) | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL | non-polymer | 767.1 | 16 | Chemie (PLX) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 20 |
| Total formula weight | 494917.1 | |
| Non-Polymers* | Number of molecules | 26 |
| Total formula weight | 24066.6 | |
| All* | Total formula weight | 518983.7 |
