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6K7Y

Intact human mitochondrial calcium uniporter complex with MICU1/MICU2 subunits

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, N...Calcium uniporter protein, mitochondrialpolymer27632300.28UniProt (Q8NE86)
Pfam (PF04678)
In PDB
Homo sapiens (Human)HsMCU,Coiled-coil domain-containing protein 109A
2E, F, G, H, R...Essential MCU regulator, mitochondrialpolymer545993.28UniProt (Q9H4I9)
Pfam (PF10161)
In PDB
Homo sapiens (Human)Single-pass membrane protein with aspartate-rich tail 1,mitochondrial
3I, VCalcium uptake protein 1, mitochondrialpolymer47654432.32UniProt (Q9BPX6)
Pfam (PF13202)
In PDB
Homo sapiens (Human)Atopy-related autoantigen CALC,ara CALC,Calcium-binding atopy-related autoantigen 1
4J, WCalcium uptake protein 2, mitochondrialpolymer33639852.72UniProt (Q8IYU8)
In PDB
Homo sapiens (Human)EF-hand domain-containing family member A1
5N, ACALCIUM IONnon-polymer40.12Chemie (CA)
6C, H, N, O, P...CARDIOLIPINnon-polymer1464.08Chemie (CDL)
7B, C, D, N, O...(9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOLnon-polymer767.116Chemie (PLX)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains20
Total formula weight494917.1
Non-Polymers*Number of molecules26
Total formula weight24066.6
All*Total formula weight518983.7
*Water molecules are not included.

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PDB entries from 2024-07-24

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