6K0W

DNA methyltransferase in complex with sinefungin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (B, A, C, D)	Adenine specific DNA methyltransferase (Mod)	polymer	618	70619.8	4	UniProt (O25315) Pfam (PF01555)	Helicobacter pylori 26695
2	E, F, G, H (B, A, C, D)	SINEFUNGIN	non-polymer		381.4	4	Chemie (SFG) PubChem (176612030) PubChem (177116271) PubChem (25246236) PubChem (46875078) PubChem (46936257) PubChem (70602121) PubChem (456189) PubChem (4065234) PubChem (65482) PubChem (70789212) PubChem (93287274) PubChem (92403972) PubChem (93287270) PubChem (93287272) PubChem (93475589) PubChem (6917665) PubChem (12771338) PubChem (12771337) PubChem (131971033) PubChem (131972810) PubChem (138626357) PubChem (156562738) PubChem (162866891) PubChem (163339130) PubChem (168280605)
3	I, J, K, L (B, A, C, D)	water	water		18.0	91	Chemie (HOH)

Sequence modifications

B, A, C, D: 1 - 598 (UniProt: O25315)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	282479.1
Non-Polymers*	Number of molecules	4
	Total formula weight	1525.5
All*	Total formula weight	284004.6

*Water molecules are not included.