6K0W

DNA methyltransferase in complex with sinefungin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0005737	cellular_component	cytoplasm
A	0008168	molecular_function	methyltransferase activity
A	0008170	molecular_function	N-methyltransferase activity
A	0009007	molecular_function	site-specific DNA-methyltransferase (adenine-specific) activity
A	0032259	biological_process	methylation
B	0003676	molecular_function	nucleic acid binding
B	0003677	molecular_function	DNA binding
B	0005737	cellular_component	cytoplasm
B	0008168	molecular_function	methyltransferase activity
B	0008170	molecular_function	N-methyltransferase activity
B	0009007	molecular_function	site-specific DNA-methyltransferase (adenine-specific) activity
B	0032259	biological_process	methylation
C	0003676	molecular_function	nucleic acid binding
C	0003677	molecular_function	DNA binding
C	0005737	cellular_component	cytoplasm
C	0008168	molecular_function	methyltransferase activity
C	0008170	molecular_function	N-methyltransferase activity
C	0009007	molecular_function	site-specific DNA-methyltransferase (adenine-specific) activity
C	0032259	biological_process	methylation
D	0003676	molecular_function	nucleic acid binding
D	0003677	molecular_function	DNA binding
D	0005737	cellular_component	cytoplasm
D	0008168	molecular_function	methyltransferase activity
D	0008170	molecular_function	N-methyltransferase activity
D	0009007	molecular_function	site-specific DNA-methyltransferase (adenine-specific) activity
D	0032259	biological_process	methylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	binding site for residue SFG B 601

Chain	Residue
B	GLY81
B	GLY408
B	SER409
B	THR411
B	GLN433
B	ILE434
B	HOH704
B	HOH705
B	ASP82
B	ASN83
B	ASP104
B	PRO380
B	LYS381
B	PHE405
B	PHE406
B	ALA407

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site_id	AC2
Number of Residues	15
Details	binding site for residue SFG A 701

Chain	Residue
A	ASP82
A	ASN83
A	ASP104
A	PHE377
A	PRO380
A	LYS381
A	PHE405
A	PHE406
A	ALA407
A	GLY408
A	SER409
A	THR411
A	GLN433
A	ILE434
A	HOH803

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site_id	AC3
Number of Residues	15
Details	binding site for residue SFG C 801

Chain	Residue
C	ASP82
C	ASN83
C	ASP104
C	PHE377
C	PRO380
C	LYS381
C	PHE406
C	ALA407
C	GLY408
C	SER409
C	THR411
C	GLN433
C	ILE434
C	HOH925
C	HOH927

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site_id	AC4
Number of Residues	15
Details	binding site for residue SFG D 901

Chain	Residue
D	ASP82
D	ASN83
D	ASP104
D	PHE377
D	PRO380
D	LYS381
D	PHE406
D	ALA407
D	GLY408
D	SER409
D	THR411
D	GLN433
D	ILE434
D	HOH1001
D	HOH1005

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Functional Information from PROSITE/UniProt

site_id	PS00092
Number of Residues	7
Details	N6_MTASE N-6 Adenine-specific DNA methylases signature. IYIDPPY

Chain	Residue	Details
B	ILE101-TYR107

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