6JXI
Rb+-bound E2-MgF state of the gastric proton pump (Tyr799Trp)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Potassium-transporting ATPase alpha chain 1 | polymer | 987 | 109220.7 | 1 | UniProt (P19156) Pfam (PF00690) Pfam (PF00122) Pfam (PF13246) Pfam (PF08282) Pfam (PF00689) | Sus scrofa (Pig) | Gastric H(+)/K(+) ATPase subunit alpha,Proton pump |
| 2 | B (B) | Potassium-transporting ATPase subunit beta | polymer | 289 | 32982.7 | 1 | UniProt (P18434) Pfam (PF00287) | Sus scrofa (Pig) | Gastric H(+)/K(+) ATPase subunit beta,Proton pump beta chain,gp60-90 |
| 3 | C (A) | TETRAFLUOROMAGNESATE(2-) | non-polymer | 100.3 | 1 | Chemie (MF4) | |||
| 4 | D, F, N, Q (A, B) | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 787.1 | 4 | Chemie (PCW) | |||
| 5 | E (A) | O-DODECANYL OCTAETHYLENE GLYCOL | non-polymer | 538.8 | 1 | Chemie (CE1) PubChem (123921) | |||
| 6 | G (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 7 | H, I, J, K, L... (A) | RUBIDIUM ION | non-polymer | 85.5 | 6 | Chemie (RB) PubChem (105153) | |||
| 8 | O, P, S, T, U (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) PubChem (24139) | |||
| 9 | R (B) | CHOLESTEROL | non-polymer | 386.7 | 1 | Chemie (CLR) PubChem (5997) | |||
| 10 | V, W (A, B) | water | water | 18.0 | 361 | Chemie (HOH) |
Sequence modifications
A: 48 - 1033 (UniProt: P19156)
B: 2 - 286 (UniProt: P18434)
| PDB | External Database | Details |
|---|---|---|
| Gly 47 | - | expression tag |
| Cys 220 | Arg 221 | engineered mutation |
| Cys 593 | Ser 594 | engineered mutation |
| Trp 799 | Tyr 800 | engineered mutation |
| Ser 1005 | Gly 1006 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Lys 287 | - | expression tag |
| Ile 288 | - | expression tag |
| Gln 289 | - | expression tag |
| Lys 290 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 142203.4 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 5817.3 | |
| All* | Total formula weight | 148020.7 |
