6JXI

Rb+-bound E2-MgF state of the gastric proton pump (Tyr799Trp)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Potassium-transporting ATPase alpha chain 1	polymer	987	109220.7	1	UniProt (P19156) Pfam (PF00690) Pfam (PF00122) Pfam (PF13246) Pfam (PF00702) Pfam (PF00689) In PDB	Sus scrofa (Pig)	Gastric H(+)/K(+) ATPase subunit alpha,Proton pump
2	B	Potassium-transporting ATPase subunit beta	polymer	289	32982.7	1	UniProt (P18434) Pfam (PF00287) In PDB	Sus scrofa (Pig)	Gastric H(+)/K(+) ATPase subunit beta,Proton pump beta chain,gp60-90
3	A	TETRAFLUOROMAGNESATE(2-)	non-polymer		100.3	1	Chemie (MF4)
4	A, B	1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE	non-polymer		787.1	4	Chemie (PCW)
5	A	O-DODECANYL OCTAETHYLENE GLYCOL	non-polymer		538.8	1	Chemie (CE1)
6	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
7	A	RUBIDIUM ION	non-polymer		85.5	6	Chemie (RB)
8	B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	5	Chemie (NAG)
9	B	CHOLESTEROL	non-polymer		386.7	1	Chemie (CLR)
10		water	water		18.0	361	Chemie (HOH)

Sequence modifications

A: 48 - 1033 (UniProt: P19156)

PDB	External Database	Details
Gly 47	-	expression tag
Cys 220	Arg 221	engineered mutation
Cys 593	Ser 594	engineered mutation
Trp 799	Tyr 800	engineered mutation
Ser 1005	Gly 1006	engineered mutation

B: 2 - 286 (UniProt: P18434)

PDB	External Database	Details
Lys 287	-	expression tag
Ile 288	-	expression tag
Gln 289	-	expression tag
Lys 290	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	142203.4
Non-Polymers*	Number of molecules	19
	Total formula weight	5817.3
All*	Total formula weight	148020.7

*Water molecules are not included.