6JVJ

Crystal structure of human MTH1 in complex with compound MI1006

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	7,8-dihydro-8-oxoguanine triphosphatase	polymer	156	17971.5	2	UniProt (P36639) Pfam (PF00293)	Homo sapiens (Human)	2-hydroxy-dATP diphosphatase,8-oxo-dGTPase,Nucleoside diphosphate-linked moiety X motif 1,Nudix motif 1
2	C, D (A, B)	5-ethyl-N4-methyl-6-piperidin-1-yl-pyrimidine-2,4-diamine	non-polymer		235.3	2	Chemie (C9L)
3	E, F (A, B)	water	water		18.0	123	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	35942.9
Non-Polymers*	Number of molecules	2
	Total formula weight	470.7
All*	Total formula weight	36413.6

*Water molecules are not included.