6JT9
Crystal Structure of D464A mutant of FGAM Synthetase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Phosphoribosylformylglycinamidine synthase | polymer | 1305 | 142666.5 | 1 | UniProt (A0A0D6F9Y3) Pfam (PF18076) Pfam (PF18072) Pfam (PF02769) Pfam (PF22689) Pfam (PF13507) UniProt (by SIFTS) (P74881) | Salmonella typhimurium | FGAMS,Formylglycinamide ribonucleotide amidotransferase,FGAR-AT |
| 2 | B, C, D (A) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 3 | E, F, G, H, I... (A) | SULFATE ION | non-polymer | 96.1 | 12 | Chemie (SO4) | |||
| 4 | Q (A) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
| 5 | R, S, T, U, V... (A) | GLYCEROL | non-polymer | 92.1 | 8 | Chemie (GOL) | |||
| 6 | AA, BA, Z (A) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 7 | CA (A) | water | water | 18.0 | 855 | Chemie (HOH) |
Sequence modifications
A: 1 - 1295 (UniProt: A0A0D6F9Y3)
| PDB | External Database | Details |
|---|---|---|
| Gly -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Gly -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Arg -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Ala 464 | Asp 464 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 142666.5 | |
| Non-Polymers* | Number of molecules | 27 |
| Total formula weight | 2496.0 | |
| All* | Total formula weight | 145162.5 |
