6JO8

The complex structure of CHIKV envelope glycoprotein bound to human MXRA8

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E (A, C, E)	Togavirin	polymer	406	45882.1	3	UniProt (C8YZ73) Pfam (PF01563) Pfam (PF00943)	Chikungunya virus (CHIKV)	CHIKV p62
2	B, D, F (B, D, F)	CHIKV E1	polymer	432	46030.8	3	UniProt (A4L787) Pfam (PF01589)	Chikungunya virus (CHIKV)
3	G, H, I (M, N, O)	Matrix remodeling-associated protein 8	polymer	269	30148.7	3	UniProt (Q9BRK3) Pfam (PF07686)	Homo sapiens (Human)	MXRA8, Limitrin
4	J, K, L (G, H, I)	2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	3	In PDB GlyTouCan (G07375KG)
5	M (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)

Sequence modifications

A, C, E: 1 - 405 (UniProt: C8YZ73)

PDB	External Database	Details
Met 0	-	expression tag

B, D, F: 1 - 412 (UniProt: A4L787)

PDB	External Database	Details
Gly -19	-	expression tag
Gly -18	-	expression tag
Gly -17	-	expression tag
Gly -16	-	expression tag
Ser -15	-	expression tag
Gly -14	-	expression tag
Gly -13	-	expression tag
Gly -12	-	expression tag
Gly -11	-	expression tag
Ser -10	-	expression tag
Gly -9	-	expression tag
Gly -8	-	expression tag
Gly -7	-	expression tag
Gly -6	-	expression tag
Ser -5	-	expression tag
Gly -4	-	expression tag
Gly -3	-	expression tag
Gly -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

M, N, O: 25 - 292 (UniProt: Q9BRK3)

PDB	External Database	Details
Met 24	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	9
	Total formula weight	366184.7
Branched	Number of molecules	3
	Total formula weight	1273.2
Non-Polymers*	Number of molecules	1
	Total formula weight	221.2
All*	Total formula weight	367679.1

*Water molecules are not included.