6JN4
Serine Beta-Lactamase KPC-2 in Complex with Dual MBL/SBL Inhibitor WL-001
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Serine Beta-Lactamase KPC-2 | polymer | 265 | 28079.6 | 4 | UniProt (Q93LQ9) Pfam (PF00144) Pfam (PF13354) UniProt (by SIFTS) (Q9F663) | Klebsiella pneumoniae | |
| 2 | E, K, R, W (A, B, C, D) | [(R)-(4-fluorophenyl)-[[(2S)-2-methyl-3-sulfanyl-propanoyl]amino]methyl]boronic acid | non-polymer | 271.1 | 4 | Chemie (BX9) | |||
| 3 | F, L, S, X (A, B, C, D) | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) | |||
| 4 | G, H, M, T, Y (A, B, C, D) | ACETIC ACID | non-polymer | 60.1 | 5 | Chemie (ACY) | |||
| 5 | I, J, N, O, P... (A, B, C) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 8 | Chemie (PEG) | |||
| 6 | AA, BA, CA, Z (B, C, D, A) | water | water | 18.0 | 657 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 26 - 291 (UniProt: Q93LQ9)
| PDB | External Database | Details |
|---|---|---|
| Ser 25 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 112318.3 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 2469.9 | |
| All* | Total formula weight | 114788.2 |
