6JMF
Crystal structure of human tyrosine-protein kinase Fes/Fps in complex with compound 4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein kinase Fes/Fps | polymer | 375 | 42483.7 | 1 | UniProt (P07332) Pfam (PF00017) Pfam (PF07714) | Homo sapiens (Human) | Feline sarcoma/Fujinami avian sarcoma oncogene homolog,Proto-oncogene c-Fes,Proto-oncogene c-Fps,p93c-fes |
| 2 | B, C (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 3 | D (A) | 6-{[(1R,2S)-2-aminocyclohexyl]amino}-5-cyano-2-[(3-methylphenyl)amino]pyridine-3-carboxamide | non-polymer | 364.4 | 1 | Chemie (9FC) | |||
| 4 | E (A) | water | water | 18.0 | 158 | Chemie (HOH) |
Sequence modifications
A: 449 - 822 (UniProt: P07332)
| PDB | External Database | Details |
|---|---|---|
| Gly 448 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42483.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 556.6 | |
| All* | Total formula weight | 43040.2 |
