6JM4

The crystal structure of PB1 homo-dimer of human P62/SQSTM1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, C)	Sequestosome-1	polymer	102	11348.9	2	UniProt (Q13501) Pfam (PF00564)	Homo sapiens (Human)	EBI3-associated protein of 60 kDa,p60,Ubiquitin-binding protein p62
2	B, C (B, D)	Sequestosome-1	polymer	102	11264.7	2	UniProt (Q13501) Pfam (PF00564)	Homo sapiens (Human)	EBI3-associated protein of 60 kDa,p60,Ubiquitin-binding protein p62

Sequence modifications

A, C: 1 - 102 (UniProt: Q13501)

PDB	External Database	Details
Ser 26	Cys 26	engineered mutation
Phe 27	Cys 27	engineered mutation
Ala 69	Asp 69	engineered mutation
Arg 71	Asp 71	engineered mutation

B, D: 1 - 102 (UniProt: Q13501)

PDB	External Database	Details
Ala 21	Arg 21	engineered mutation
Ser 26	Cys 26	engineered mutation
Phe 27	Cys 27	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	45227.2
All*	Total formula weight	45227.2

*Water molecules are not included.