6JKI
Crystal structure and catalytic mechanism of the essential m1G37 tRNA methyltransferase TrmD from Pseudomonas aeruginosa
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | tRNA (guanine-N(1)-)-methyltransferase | polymer | 250 | 28066.7 | 2 | UniProt (Q02RL6) Pfam (PF01746) UniProt (by SIFTS) (Q9HXQ1) | Pseudomonas aeruginosa | M1G-methyltransferase,tRNA [GM37] methyltransferase |
| 2 | C, H (A) | SINEFUNGIN | non-polymer | 381.4 | 2 | Chemie (SFG) | |||
| 3 | D, E, F, G, M... (A, B) | GLYCEROL | non-polymer | 92.1 | 10 | Chemie (GOL) | |||
| 4 | I, J, T (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 3 | Chemie (MN) | |||
| 5 | K, U (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 6 | L, P (B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 7 | V, W (A, B) | water | water | 18.0 | 135 | Chemie (HOH) |
Sequence modifications
A, B: 5 - 252 (UniProt: Q02RL6)
| PDB | External Database | Details |
|---|---|---|
| Ser 3 | - | expression tag |
| Met 4 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 56133.3 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 2106.7 | |
| All* | Total formula weight | 58240.1 |
