6JKE
Discovery and the crystal structure of NS5 in complex with the N-terminal bromodomain of BRD2.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Bromodomain-containing protein 2 | polymer | 122 | 14471.9 | 3 | UniProt (P25440) Pfam (PF00439) In PDB | Homo sapiens (Human) | O27.1.1,Really interesting new gene 3 protein |
| 2 | A | 7-chloranyl-2-[(3-chlorophenyl)amino]pyrano[3,4-e][1,3]oxazine-4,5-dione | non-polymer | 325.1 | 1 | Chemie (BUX) | |||
| 3 | A, C | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | A | 2,3-DIHYDROXY-1,4-DITHIOBUTANE | non-polymer | 154.3 | 1 | Chemie (DTT) | |||
| 5 | B | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | B, C | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 7 | B | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 8 | water | water | 18.0 | 465 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 43415.6 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1070.0 | |
| All* | Total formula weight | 44485.6 |
