6JK6
Crystal structure of human chitotriosidase-1 (hCHIT) catalytic domain in complex with compound 2-8-s2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Chitotriosidase-1 | polymer | 381 | 42668.7 | 1 | UniProt (Q13231) Pfam (PF00704) | Homo sapiens (Human) | Chitinase-1 |
| 2 | B, C (A) | 6-azanyl-11-methyl-2-oxidanylidene-7-[[(2R)-oxolan-2-yl]methyl]-N-(pyridin-3-ylmethyl)-1,9-diaza-7-azoniatricyclo[8.4.0.0^{3,8}]tetradeca-3(8),4,6,9,11,13-hexaene-5-carboxamide | non-polymer | 445.5 | 2 | Chemie (BV0) | |||
| 3 | D (A) | water | water | 18.0 | 355 | Chemie (HOH) |
Sequence modifications
A: 22 - 396 (UniProt: Q13231)
| PDB | External Database | Details |
|---|---|---|
| His 397 | - | expression tag |
| His 398 | - | expression tag |
| His 399 | - | expression tag |
| His 400 | - | expression tag |
| His 401 | - | expression tag |
| His 402 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42668.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 891.0 | |
| All* | Total formula weight | 43559.7 |
