6JIB
Human MTHFD2 in complex with DS44960156
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial | polymer | 323 | 35215.5 | 2 | UniProt (P13995) Pfam (PF00763) Pfam (PF02882) In PDB | Homo sapiens (Human) | |
2 | A, B | 4-(5-oxo-1,5-dihydro-2H-[1]benzopyrano[3,4-c]pyridine-3(4H)-carbonyl)benzoic acid | non-polymer | 349.3 | 4 | Chemie (BQF) | |||
3 | A | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
4 | A, B | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
5 | water | water | 18.0 | 141 | Chemie (HOH) |
Sequence modifications
A, B: 36 - 338 (UniProt: P13995)
PDB | External Database | Details |
---|---|---|
Met 16 | - | expression tag |
Gly 17 | - | expression tag |
Ser 18 | - | expression tag |
Ser 19 | - | expression tag |
His 20 | - | expression tag |
His 21 | - | expression tag |
His 22 | - | expression tag |
His 23 | - | expression tag |
His 24 | - | expression tag |
His 25 | - | expression tag |
Ser 26 | - | expression tag |
Ser 27 | - | expression tag |
Gly 28 | - | expression tag |
Glu 29 | - | expression tag |
Asn 30 | - | expression tag |
Leu 31 | - | expression tag |
Tyr 32 | - | expression tag |
Phe 33 | - | expression tag |
Gln 34 | - | expression tag |
Gly 35 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 70430.9 | |
Non-Polymers* | Number of molecules | 11 |
Total formula weight | 2047.8 | |
All* | Total formula weight | 72478.7 |