6JHP

Crystal structure of the glycoside hydrolase family 36 alpha-galactosidase from Paecilomyces thermophila

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Alpha-galactosidase	polymer	758	83900.7	4	UniProt (A0A2Z4HIN9) Pfam (PF16875) Pfam (PF02065) Pfam (PF16874)	Paecilomyces sp. 'thermophila'
2	E, F, G, H (A, B, C)	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	4	Chemie (TRS)
3	I, J, K, L (A, B, C, D)	water	water		18.0	325	Chemie (HOH)

Sequence modifications

A, B, C, D: 27 - 748 (UniProt: A0A2Z4HIN9)

PDB	External Database	Details
Met -9	-	initiating methionine
Gly -8	-	expression tag
Ser -7	-	expression tag
Ser -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Ser 1	-	expression tag
Ser 2	-	expression tag
Gly 3	-	expression tag
Leu 4	-	expression tag
Val 5	-	expression tag
Pro 6	-	expression tag
Arg 7	-	expression tag
Gly 8	-	expression tag
Ser 9	-	expression tag
His 10	-	expression tag
Met 11	-	expression tag
Ala 12	-	expression tag
Ser 13	-	expression tag
Met 14	-	expression tag
Thr 15	-	expression tag
Gly 16	-	expression tag
Gly 17	-	expression tag
Gln 18	-	expression tag
Gln 19	-	expression tag
Met 20	-	expression tag
Gly 21	-	expression tag
Arg 22	-	expression tag
Gly 23	-	expression tag
Ser 24	-	expression tag
Glu 25	-	expression tag
Phe 26	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	335602.7
Non-Polymers*	Number of molecules	4
	Total formula weight	488.6
All*	Total formula weight	336091.2

*Water molecules are not included.