6JCL

Crystal structure of cofactor-bound Rv0187 from MTB

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, G...)	Probable O-methyltransferase	polymer	235	24914.2	8	UniProt (O07431) Pfam (PF01596)	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
2	EA, GA, I, IA, N... (H, E, A, F, B...)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	8	Chemie (SAH)
3	AA, CA, DA, J, L... (G, A, B, D)	STRONTIUM ION	non-polymer		87.6	10	Chemie (SR)
4	BA, FA, HA, JA, K... (G, H, E, F, A...)	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	9	Chemie (MPD)
5	R (B)	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
6	KA, LA, MA, NA, OA... (A, B, C, D, G...)	water	water		18.0	873	Chemie (HOH)

Sequence modifications

A, B, C, D, G, H, E, F: 1 - 220 (UniProt: O07431)

PDB	External Database	Details
Glu 221	-	expression tag
Asn 222	-	expression tag
Leu 223	-	expression tag
Tyr 224	-	expression tag
Phe 225	-	expression tag
Gln 226	-	expression tag
Gly 227	-	expression tag
Gly 228	-	expression tag
His 229	-	expression tag
His 230	-	expression tag
His 231	-	expression tag
His 232	-	expression tag
His 233	-	expression tag
His 234	-	expression tag
Gly 235	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	199313.8
Non-Polymers*	Number of molecules	28
	Total formula weight	5038.0
All*	Total formula weight	204351.9

*Water molecules are not included.