6JCK
Complex structure of Axin-DIX and Dvl2-DIX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Axin-1 | polymer | 82 | 9471.8 | 1 | UniProt (O15169) Pfam (PF00778) In PDB | Homo sapiens (Human) | Axis inhibition protein 1,hAxin |
| 2 | B | Segment polarity protein dishevelled homolog DVL-2 | polymer | 82 | 9218.4 | 1 | UniProt (O14641) Pfam (PF00778) In PDB | Homo sapiens (Human) | Dishevelled-2,DSH homolog 2 |
Sequence modifications
A: 745 - 826 (UniProt: O15169)
B: 12 - 93 (UniProt: O14641)
| PDB | External Database | Details |
|---|---|---|
| Asp 760 | Tyr 760 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ala 67 | Val 67 | engineered mutation |
| Ala 68 | Lys 68 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 18690.2 | |
| All* | Total formula weight | 18690.2 |
