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6JAT

Crystal structure of SETD3 bound to Actin peptide and SFG

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, CHistone-lysine N-methyltransferase setd3polymer49957223.02UniProt (Q86TU7)
Pfam (PF00856)
Pfam (PF09273)
In PDB
Homo sapiens (Human)SET domain-containing protein 3
2B, DActin, gamma-enteric smooth musclepolymer222573.92UniProt (P63267)
In PDB
Homo sapiensAlpha-actin-3,Gamma-2-actin,Smooth muscle gamma-actin
3A, CSINEFUNGINnon-polymer381.42Chemie (SFG)
4A, CSULFATE IONnon-polymer96.15Chemie (SO4)
5C4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACIDnon-polymer238.31Chemie (EPE)
6waterwater18.084Chemie (HOH)
Sequence modifications
A, C: 0 - 497 (UniProt: Q86TU7)
PDBExternal DatabaseDetails
Ser -1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight119593.9
Non-Polymers*Number of molecules8
Total formula weight1481.4
All*Total formula weight121075.3
*Water molecules are not included.

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PDB entries from 2024-10-02

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