6J6X

Crystal structure of apo GGTaseIII

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Protein prenyltransferase alpha subunit repeat-containing protein 1	polymer	366	42228.9	1	UniProt (Q7Z6K3) Pfam (PF01239)	Homo sapiens (Human)
2	B (B)	Geranylgeranyl transferase type-2 subunit beta	polymer	336	37371.7	1	UniProt (P53611) Pfam (PF00432)	Homo sapiens (Human)	Geranylgeranyl transferase type II subunit beta,GGTase-II-beta,Rab geranyl-geranyltransferase subunit beta,Rab GGTase beta,Rab geranylgeranyltransferase subunit beta,Type II protein geranyl-geranyltransferase subunit beta
3	C, E (A, B)	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	2	Chemie (MPD)
4	D (B)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)

Sequence modifications

A: 1 - 366 (UniProt: Q7Z6K3)

PDB	External Database	Details
Gly 328	-	insertion
Arg 329	-	insertion
Phe 330	-	insertion
Pro 331	-	insertion
His 332	-	insertion
Ser 333	-	insertion
Met 334	-	insertion
Thr 335	-	insertion
Gln 336	-	insertion
Leu 337	-	insertion
Ser 338	-	insertion
Pro 339	-	insertion
Ala 340	-	insertion
Asp 341	-	insertion
Ser 342	-	insertion
Pro 343	-	insertion
Gly 344	-	insertion
Gly 345	-	insertion
Thr 346	-	insertion
Leu 347	-	insertion
Ser 348	-	insertion
Asp 349	-	insertion
Leu 350	-	insertion
His 351	-	insertion
Leu 352	-	insertion
Ile 353	-	insertion
Pro 354	-	insertion

B: 1 - 331 (UniProt: P53611)

PDB	External Database	Details
Gly -4	-	expression tag
Pro -3	-	expression tag
Leu -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	79600.7
Non-Polymers*	Number of molecules	3
	Total formula weight	260.7
All*	Total formula weight	79861.3

*Water molecules are not included.