6J64
Crystal structure of human HINT1 mutant complexing with AP4A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Histidine triad nucleotide-binding protein 1 | polymer | 128 | 13957.1 | 2 | UniProt (P49773) Pfam (PF01230) In PDB | Homo sapiens (Human) | Adenosine 5'-monophosphoramidase,Protein kinase C inhibitor 1,Protein kinase C-interacting protein 1,PKCI-1 |
| 2 | B | 2-AMINOETHANESULFONIC ACID | non-polymer | 125.1 | 1 | Chemie (TAU) | |||
| 3 | B | BIS(ADENOSINE)-5'-TETRAPHOSPHATE | non-polymer | 836.4 | 1 | Chemie (B4P) | |||
| 4 | water | water | 18.0 | 509 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 126 (UniProt: P49773)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| Leu 0 | - | expression tag |
| Ala 114 | His 114 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27914.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 961.5 | |
| All* | Total formula weight | 28875.7 |
