6J5Z
Crystal structure of human HINT1 mutant complexing with AP3A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Histidine triad nucleotide-binding protein 1 | polymer | 128 | 13957.1 | 4 | UniProt (P49773) Pfam (PF01230) | Homo sapiens (Human) | Adenosine 5'-monophosphoramidase,Protein kinase C inhibitor 1,Protein kinase C-interacting protein 1,PKCI-1 |
| 2 | E (A) | ETHANESULFONIC ACID | non-polymer | 110.1 | 1 | Chemie (ESA) | |||
| 3 | F, G (A, D) | ADENOSINE | non-polymer | 267.2 | 2 | Chemie (ADN) | |||
| 4 | H, I, J, K (A, B, C, D) | water | water | 18.0 | 747 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 126 (UniProt: P49773)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| Leu 0 | - | expression tag |
| Ala 114 | His 114 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 55828.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 644.6 | |
| All* | Total formula weight | 56473.0 |
