6IZX
The RNA-dependent RNA polymerase domain of dengue 2 NS5, bound with RK-0404678
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Genome polyprotein | polymer | 686 | 79627.0 | 1 | UniProt (C6L435) Pfam (PF00972) Pfam (PF20483) UniProt (by SIFTS) (P14340) | Dengue virus 2 | DENV2 RdRp |
| 2 | B, C (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, E, F, G, H... (A) | COBALT (II) ION | non-polymer | 58.9 | 9 | Chemie (CO) | |||
| 4 | M, N (A) | 2-oxo-2H-1,3-benzoxathiol-5-yl acetate | non-polymer | 210.2 | 2 | Chemie (B5C) | |||
| 5 | O (A) | water | water | 18.0 | 206 | Chemie (HOH) |
Sequence modifications
A: 251 - 896 (UniProt: C6L435)
| PDB | External Database | Details |
|---|---|---|
| Met 211 | - | initiating methionine |
| Lys 212 | - | expression tag |
| Asp 213 | - | expression tag |
| His 214 | - | expression tag |
| Leu 215 | - | expression tag |
| Ile 216 | - | expression tag |
| His 217 | - | expression tag |
| Asn 218 | - | expression tag |
| His 219 | - | expression tag |
| His 220 | - | expression tag |
| Lys 221 | - | expression tag |
| His 222 | - | expression tag |
| Glu 223 | - | expression tag |
| His 224 | - | expression tag |
| Ala 225 | - | expression tag |
| His 226 | - | expression tag |
| Ala 227 | - | expression tag |
| Glu 228 | - | expression tag |
| His 229 | - | expression tag |
| Asp 230 | - | expression tag |
| Tyr 231 | - | expression tag |
| Lys 232 | - | expression tag |
| Asp 233 | - | expression tag |
| Asp 234 | - | expression tag |
| Asp 235 | - | expression tag |
| Asp 236 | - | expression tag |
| Lys 237 | - | expression tag |
| Glu 238 | - | expression tag |
| His 239 | - | expression tag |
| Leu 240 | - | expression tag |
| Tyr 241 | - | expression tag |
| Phe 242 | - | expression tag |
| Gln 243 | - | expression tag |
| Gly 244 | - | See Sequence Details |
| Ser 245 | - | See Sequence Details |
| Ser 246 | - | See Sequence Details |
| Gly 247 | - | See Sequence Details |
| Ser 248 | - | See Sequence Details |
| Ser 249 | - | See Sequence Details |
| Gly 250 | - | See Sequence Details |
| Val 628 | Ile 3119 | See Sequence Details |
| Arg 749 | Lys 3240 | See Sequence Details |
| Ile 836 | Val 3327 | See Sequence Details |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 79627.0 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1081.6 | |
| All* | Total formula weight | 80708.7 |
