6IZX

The RNA-dependent RNA polymerase domain of dengue 2 NS5, bound with RK-0404678

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003968	molecular_function	RNA-directed RNA polymerase activity
A	0005524	molecular_function	ATP binding
A	0039694	biological_process	viral RNA genome replication

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 901

Chain	Residue
A	GLU438
A	HIS442
A	CYS447
A	CYS450

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site_id	AC2
Number of Residues	3
Details	binding site for residue ZN A 902

Chain	Residue
A	HIS714
A	CYS728
A	ARG842

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site_id	AC3
Number of Residues	5
Details	binding site for residue CO A 903

Chain	Residue
A	HOH1047
A	HOH1189
A	HOH1195
A	THR606
A	HOH1036

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site_id	AC4
Number of Residues	1
Details	binding site for residue CO A 904

Chain	Residue
A	SER291

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site_id	AC5
Number of Residues	3
Details	binding site for residue CO A 905

Chain	Residue
A	LYS548
A	ARG596
A	HOH1188

---

site_id	AC6
Number of Residues	1
Details	binding site for residue CO A 907

Chain	Residue
A	GLY537

---

site_id	AC7
Number of Residues	1
Details	binding site for residue CO A 908

Chain	Residue
A	THR311

---

site_id	AC8
Number of Residues	1
Details	binding site for residue CO A 909

Chain	Residue
A	TRP803

---

site_id	AC9
Number of Residues	1
Details	binding site for residue CO A 910

Chain	Residue
A	TRP823

---

site_id	AD1
Number of Residues	1
Details	binding site for residue CO A 911

Chain	Residue
A	GLY559

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site_id	AD2
Number of Residues	5
Details	binding site for residue B5C A 912

Chain	Residue
A	VAL507
A	GLU510
A	GLY511
A	SER661
A	CYS709

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site_id	AD3
Number of Residues	9
Details	binding site for residue B5C A 913

Chain	Residue
A	GLN760
A	SER763
A	ARG773
A	ASN777
A	CYS780
A	MET809
A	TRP833
A	TYR882
A	HOH1072

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q6YMS4","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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