6IZM
Crystal structure of the PPARgamma-LBD complexed with compound 1l
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Peroxisome proliferator-activated receptor gamma | polymer | 283 | 32412.6 | 1 | UniProt (P37231) Pfam (PF00104) In PDB | Homo sapiens (Human) | PPAR-gamma,Nuclear receptor subfamily 1 group C member 3 |
2 | C | Peptide from Peroxisome proliferator-activated receptor gamma coactivator 1-alpha | polymer | 19 | 2067.4 | 1 | UniProt (Q9UBK2) In PDB | Homo sapiens | PPARGC-1-alpha,Ligand effect modulator 6 |
3 | A | 3-[[6-(2,6-dimethylpyridin-3-yl)oxy-1-methyl-benzimidazol-2-yl]methoxy]benzoic acid | non-polymer | 403.4 | 1 | Chemie (B0X) | |||
4 | water | water | 18.0 | 171 | Chemie (HOH) |
Sequence modifications
A: 206 - 477 (UniProt: P37231)
PDB | External Database | Details |
---|---|---|
Met 195 | - | expression tag |
Arg 196 | - | expression tag |
Gly 197 | - | expression tag |
Ser 198 | - | expression tag |
His 199 | - | expression tag |
His 200 | - | expression tag |
His 201 | - | expression tag |
His 202 | - | expression tag |
His 203 | - | expression tag |
His 204 | - | expression tag |
Gly 205 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 34480.0 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 403.4 | |
All* | Total formula weight | 34883.4 |