6IWG
Crystal structure of rhesus macaque MHC class I molecule Mamu-B*05104 complexed with N-myristoylated 4-mer lipopeptide derived from SIV nef protein
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | MHC class I antigen | polymer | 276 | 31919.1 | 1 | UniProt (B2ZHY7) Pfam (PF00129) Pfam (PF07654) | Macaca mulatta (Rhesus macaque) | Major histocompatibility complex class I,MHC-class I protein |
| 2 | B (B) | Beta-2-microglobulin | polymer | 100 | 11731.2 | 1 | UniProt (Q6V7J5) Pfam (PF07654) | Macaca mulatta (Rhesus macaque) | |
| 3 | C (C) | N-myristoylated 4-mer lipopeptide | polymer | 5 | 526.7 | 1 | Simian immunodeficiency virus | ||
| 4 | D, E, F, R (A, B) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 5 | G, H, I, J, K... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 18 | Chemie (EDO) | |||
| 6 | AA, BA, Q (B, A) | BORIC ACID | non-polymer | 61.8 | 3 | Chemie (BO3) | |||
| 7 | CA, DA, EA (A, B, C) | water | water | 18.0 | 304 | Chemie (HOH) |
Sequence modifications
A: 1 - 276 (UniProt: B2ZHY7)
| PDB | External Database | Details |
|---|---|---|
| Glu 128 | Arg 149 | engineered mutation |
| Glu 177 | Lys 198 | engineered mutation |
| Glu 223 | Asp 244 | engineered mutation |
| Glu 264 | Lys 285 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 44177.0 | |
| Non-Polymers* | Number of molecules | 25 |
| Total formula weight | 1394.7 | |
| All* | Total formula weight | 45571.6 |
