6IUI

Crystal structure of GIT1 PBD domain in complex with Paxillin LD4 motif

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	ARF GTPase-activating protein GIT1	polymer	132	14692.9	2	UniProt (Q9Z272) Pfam (PF12205) In PDB	Rattus norvegicus (Rat)	ARF GAP GIT1,Cool-associated and tyrosine-phosphorylated protein 1,CAT1,G protein-coupled receptor kinase-interactor 1,GRK-interacting protein 1
2	C, D	Paxillin	polymer	28	3024.3	2	UniProt (B4DRY6) UniProt (by SIFTS) (P49023) In PDB	Homo sapiens (Human)

Sequence modifications

A, B: 645 - 770 (UniProt: Q9Z272)

PDB	External Database	Details
Gly 639	-	expression tag
Pro 640	-	expression tag
Gly 641	-	expression tag
Ser 642	-	expression tag
Glu 643	-	expression tag
Phe 644	-	expression tag

C, D: 261 - 282 (UniProt: B4DRY6)

PDB	External Database	Details
Gly 255	-	expression tag
Pro 256	-	expression tag
Gly 257	-	expression tag
Ser 258	-	expression tag
Glu 259	-	expression tag
Phe 260	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	35434.4
All*	Total formula weight	35434.4

*Water molecules are not included.