6IUA
Crystal structure of importin-alpha1 bound to the 53BP1 nuclear localization signal (S1678D)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Importin subunit alpha-1 | polymer | 427 | 46243.0 | 1 | UniProt (P52293) Pfam (PF01749) Pfam (PF00514) Pfam (PF16186) | Mus musculus (Mouse) | Importin alpha P1,Karyopherin subunit alpha-2,Pendulin,Pore targeting complex 58 kDa subunit,PTAC58,RAG cohort protein 1,SRP1-alpha |
| 2 | B (B) | Peptide from TP53-binding protein 1 | polymer | 22 | 2536.9 | 1 | UniProt (Q12888) | Homo sapiens (Human) | p53BP1 |
| 3 | C, D (A, B) | water | water | 18.0 | 475 | Chemie (HOH) |
Sequence modifications
B: 1665 - 1686 (UniProt: Q12888)
| PDB | External Database | Details |
|---|---|---|
| Asp 1678 | Ser 1678 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 48779.8 | |
| All* | Total formula weight | 48779.8 |
