6ITO
Crystal structure of pyruvate kinase (PYK) from Mycobacterium tuberculosis in complex with Oxalate, AMP and inhibitor Ribose 5-Phosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Pyruvate kinase | polymer | 475 | 51014.3 | 4 | UniProt (P9WKE5) Pfam (PF00224) Pfam (PF02887) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | PK |
| 2 | E, I, M, Q (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 3 | F, J, N, R (A, B, C, D) | OXALATE ION | non-polymer | 88.0 | 4 | Chemie (OXL) | |||
| 4 | G, K, O, S (A, B, C, D) | RIBOSE-5-PHOSPHATE | non-polymer | 230.1 | 4 | Chemie (R5P) | |||
| 5 | H, L, P, T (A, B, C, D) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 4 | Chemie (AMP) | |||
| 6 | U, V, W, X (A, B, C, D) | water | water | 18.0 | 540 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 472 (UniProt: P9WKE5)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Gly -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 204057.3 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 2758.6 | |
| All* | Total formula weight | 206816.0 |
