6IRW

Crystal structure of the human cap-specific adenosine methyltransferase bound to SAH

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Phosphorylated CTD-interacting factor 1	polymer	508	59393.0	2	UniProt (Q9H4Z3) Pfam (PF12237) In PDB	Homo sapiens (Human)
2	A, B	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	2	Chemie (SAH)
3		water	water		18.0	19	Chemie (HOH)

Sequence modifications

A, B: 174 - 672 (UniProt: Q9H4Z3)

PDB	External Database	Details
Glu 165	-	expression tag
Asn 166	-	expression tag
Leu 167	-	expression tag
Tyr 168	-	expression tag
Phe 169	-	expression tag
Gln 170	-	expression tag
Gly 171	-	expression tag
Ser 172	-	expression tag
His 173	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	118786.1
Non-Polymers*	Number of molecules	2
	Total formula weight	768.8
All*	Total formula weight	119554.9

*Water molecules are not included.