6IRG

Structure of the human GluN1/GluN2A NMDA receptor in the glutamate/glycine-bound state at pH 6.3, Class II

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	C, A	Glutamate receptor ionotropic, NMDA 1	polymer	847	95336.2	2	UniProt (Q05586) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) In PDB	Homo sapiens (Human)	N-methyl-D-aspartate receptor subunit NR1,NMD-R1
2	B, D	Glutamate receptor ionotropic, NMDA 2A	polymer	841	94192.2	2	UniProt (Q12879) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) In PDB	Homo sapiens (Human)	N-methyl D-aspartate receptor subtype 2A,hNR2A

Sequence modifications

C, A: 1 - 847 (UniProt: Q05586)

PDB	External Database	Details
Arg 612	Gly 612	engineered mutation

B, D: 1 - 841 (UniProt: Q12879)

PDB	External Database	Details
Arg 656	Glu 656	engineered mutation
Arg 657	Glu 657	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	379056.8
All*	Total formula weight	379056.8

*Water molecules are not included.