6IQN
Crystal structure of TrkA kinase with ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | High affinity nerve growth factor receptor | polymer | 296 | 33617.8 | 2 | UniProt (P04629) Pfam (PF07714) | Homo sapiens (Human) | Neurotrophic tyrosine kinase receptor type 1,TRK1-transforming tyrosine kinase protein,Tropomyosin-related kinase A,Tyrosine kinase receptor,Tyrosine kinase receptor A,Trk-A,gp140trk,p140-TrkA |
| 2 | C, D (A, B) | 4-[[4-azanyl-3-(4-cyclohexylpiperazin-1-yl)-9,10-bis(oxidanylidene)anthracen-1-yl]amino]benzoic acid | non-polymer | 524.6 | 2 | Chemie (AQ6) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 91 | Chemie (HOH) |
Sequence modifications
A, B: 502 - 796 (UniProt: P04629)
| PDB | External Database | Details |
|---|---|---|
| Ser 501 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 67235.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1049.2 | |
| All* | Total formula weight | 68284.9 |
