6IQ5
Crystal Structure of CYP1B1 and Inhibitor Having Azide Group
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Cytochrome P450 1B1 | polymer | 463 | 52266.6 | 2 | UniProt (Q16678) Pfam (PF00067) In PDB | Homo sapiens (Human) | CYPIB1 |
| 2 | A, B | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 3 | A | 2-(cis-4-azidocyclohexyl)-4H-naphtho[1,2-b]pyran-4-one | non-polymer | 319.4 | 1 | Chemie (AQ0) | |||
| 4 | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
A, B: 68 - 530 (UniProt: Q16678)
| PDB | External Database | Details |
|---|---|---|
| Ser 119 | Ala 119 | variant |
| Val 432 | Leu 432 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 104533.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1552.3 | |
| All* | Total formula weight | 106085.6 |
