Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| A | 0020037 | molecular_function | heme binding |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0005506 | molecular_function | iron ion binding |
| B | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| B | 0020037 | molecular_function | heme binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | binding site for residue HEM A 901 |
| Chain | Residue |
| A | ARG117 |
| A | LEU335 |
| A | PHE394 |
| A | VAL395 |
| A | THR398 |
| A | ILE399 |
| A | HIS401 |
| A | GLN424 |
| A | ILE462 |
| A | PHE463 |
| A | SER464 |
| A | ALA133 |
| A | ARG468 |
| A | CYS470 |
| A | GLY472 |
| A | SER476 |
| A | TRP141 |
| A | ARG145 |
| A | MET152 |
| A | ILE327 |
| A | ALA330 |
| A | SER331 |
| A | THR334 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | binding site for residue AQ0 A 902 |
| Chain | Residue |
| A | VAL126 |
| A | ASN228 |
| A | PHE231 |
| A | LEU264 |
| A | PHE268 |
| A | ASP326 |
| A | GLY329 |
| A | ALA330 |
| A | THR334 |
| A | VAL395 |
| A | ILE399 |
| A | LEU509 |
| A | THR510 |
| site_id | AC3 |
| Number of Residues | 21 |
| Details | binding site for residue HEM B 900 |
| Chain | Residue |
| B | ARG117 |
| B | MET132 |
| B | ALA133 |
| B | ARG145 |
| B | ILE327 |
| B | ALA330 |
| B | SER331 |
| B | THR334 |
| B | PHE394 |
| B | VAL395 |
| B | THR398 |
| B | ILE399 |
| B | HIS401 |
| B | ILE462 |
| B | PHE463 |
| B | SER464 |
| B | ARG468 |
| B | CYS470 |
| B | ILE471 |
| B | GLY472 |
| B | SER476 |
Functional Information from PROSITE/UniProt
| site_id | PS00086 |
| Number of Residues | 10 |
| Details | CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FSvGKRRCIG |
| Chain | Residue | Details |
| A | PHE463-GLY472 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"21147782","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3PM0","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Site: {"description":"Major determinant of CYP1B1 17beta-estradiol hydroxylation regiospecificity"} |
