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6IJR

Human PPARgamma ligand binding domain complexed with SB1495

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, C)
Peroxisome proliferator-activated receptor gammapolymer28332280.32UniProt (P37231)
Pfam (PF00104)
Homo sapiens (Human)PPAR-gamma,Nuclear receptor subfamily 1 group C member 3
2B, D
(B, D)
16 mer peptide from Nuclear receptor coactivator 1polymer161905.22UniProt (Q15788)Homo sapiens
3E, F
(A, C)
N-{[3-({[(1S,2R)-2-{[(2E)-2-cyano-4,4-dimethylpent-2-enoyl]amino}cyclopentyl]oxy}methyl)phenyl]methyl}-4-[(4-methylpiperazin-1-yl)methyl]benzamidenon-polymer571.82Chemie (A9C)
4G, H
(A, C)
waterwater18.024Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight68371.1
Non-Polymers*Number of molecules2
Total formula weight1143.5
All*Total formula weight69514.6
*Water molecules are not included.

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PDB entries from 2025-06-18

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