6IH0
Aquifex aeolicus LpxC complex with ACHN-975
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | UDP-3-O-acyl-N-acetylglucosamine deacetylase | polymer | 279 | 32060.7 | 1 | UniProt (O67648) Pfam (PF03331) | Aquifex aeolicus (strain VF5) | UDP-3-O-acyl-GlcNAc deacetylase,UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase |
| 2 | B (A) | N-[(2S)-3-azanyl-3-methyl-1-(oxidanylamino)-1-oxidanylidene-butan-2-yl]-4-[4-[(1R,2R)-2-(hydroxymethyl)cyclopropyl]buta -1,3-diynyl]benzamide | non-polymer | 369.4 | 1 | Chemie (A5F) | |||
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (A) | methyl (2S)-2-azanyl-3-methyl-3-[(2-methylpropan-2-yl)oxycarbonylamino]butanoate | non-polymer | 246.3 | 1 | Chemie (A5U) | |||
| 5 | E (A) | water | water | 18.0 | 350 | Chemie (HOH) |
Sequence modifications
A: 1 - 271 (UniProt: O67648)
| PDB | External Database | Details |
|---|---|---|
| Ala 181 | Cys 181 | conflict |
| Leu 272 | - | expression tag |
| Glu 273 | - | expression tag |
| His 274 | - | expression tag |
| His 275 | - | expression tag |
| His 276 | - | expression tag |
| His 277 | - | expression tag |
| His 278 | - | expression tag |
| His 279 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32060.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 681.1 | |
| All* | Total formula weight | 32741.8 |
