6IEU
The structure of TRIM66 PHD-Bromo domain with unmodified H3 N terminal peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tripartite motif-containing protein 66 | polymer | 196 | 22607.8 | 1 | UniProt (O15016) Pfam (PF00628) Pfam (PF00439) | Homo sapiens (Human) | |
| 2 | B (C) | ALA-ARG-THR-LYS-GLN-THR-ALA-ARG-LYS-SER-THR-GLY | polymer | 12 | 1308.5 | 1 | UniProt (by SIFTS) (P68431) | Homo sapiens | |
| 3 | C, D (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | E, F (A, C) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | G, H (A, C) | water | water | 18.0 | 106 | Chemie (HOH) |
Sequence modifications
A: 968 - 1160 (UniProt: O15016)
| PDB | External Database | Details |
|---|---|---|
| Pro 965 | - | expression tag |
| His 966 | - | expression tag |
| Met 967 | - | expression tag |
| Thr 1002 | Leu 1002 | engineered mutation |
| Ser 1026 | Cys 1026 | engineered mutation |
| Ser 1030 | Cys 1030 | engineered mutation |
| His 1031 | Tyr 1031 | engineered mutation |
| Lys 1036 | Met 1036 | engineered mutation |
| Thr 1089 | Ile 1089 | engineered mutation |
| Ser 1135 | Cys 1135 | engineered mutation |
| Asn 1138 | Val 1138 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 23916.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 315.0 | |
| All* | Total formula weight | 24231.3 |
