6IET

The crystal structure of TRIM66 PHD-Bromo domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Tripartite motif-containing protein 66	polymer	196	22607.8	1	UniProt (O15016) Pfam (PF00628) Pfam (PF00439) In PDB	Homo sapiens (Human)
2	A	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
3		water	water		18.0	56	Chemie (HOH)

Sequence modifications

A: 968 - 1160 (UniProt: O15016)

PDB	External Database	Details
Pro 965	-	expression tag
His 966	-	expression tag
Met 967	-	expression tag
Thr 1002	Leu 1002	engineered mutation
Ser 1026	Cys 1026	engineered mutation
Ser 1030	Cys 1030	engineered mutation
His 1031	Tyr 1031	engineered mutation
Lys 1036	Met 1036	engineered mutation
Thr 1089	Ile 1089	engineered mutation
Ser 1135	Cys 1135	engineered mutation
Asn 1138	Val 1138	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	22607.8
Non-Polymers*	Number of molecules	2
	Total formula weight	130.8
All*	Total formula weight	22738.6

*Water molecules are not included.