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6IEH

Crystal structures of the hMTR4-NRDE2 complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(B)
Exosome RNA helicase MTR4polymer979111188.41UniProt (P42285)
Pfam (PF00270)
Pfam (PF00271)
Pfam (PF21408)
Pfam (PF13234)
Pfam (PF08148)
Homo sapiens (Human)ATP-dependent RNA helicase DOB1,ATP-dependent RNA helicase SKIV2L2,Superkiller viralicidic activity 2-like 2,TRAMP-like complex helicase
2B
(A)
Protein NRDE2 homologpolymer10511886.51UniProt (Q9H7Z3)Homo sapiens (Human)
3C
(B)
CHLORIDE IONnon-polymer35.51Chemie (CL)
4D
(B)
ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.21Chemie (ATP)
5E, F
(B, A)
waterwater18.032Chemie (HOH)
Sequence modifications
B: 71 - 1042 (UniProt: P42285)
PDBExternal DatabaseDetails
Gly 64-expression tag
Ala 65-expression tag
Met 66-expression tag
Asp 67-expression tag
Pro 68-expression tag
Glu 69-expression tag
Phe 70-expression tag
A: 163 - 266 (UniProt: Q9H7Z3)
PDBExternal DatabaseDetails
Ser 162-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight123074.9
Non-Polymers*Number of molecules2
Total formula weight542.6
All*Total formula weight123617.5
*Water molecules are not included.

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PDB entries from 2025-06-11

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